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Filtered Search Results
Cayman Chemical GlycIdyl PalmItate 50mg
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A glycidyl fatty acid ester; has been found in palm and corn oils
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Medchemexpress LLC Itaconate-alkyne | 2454181-83-8 | 98.0% | C13H18O4 | 10MG
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Itaconate-alkyne is an alkyne-tagged bioorthogonal probe designed for quantitative and site-specific chemoproteomic profiling of itaconation in living cells. As a functional analogue of itaconate, it enables labeling of bona fide itaconate targets and is compatible with click-chemistry workflows.
- Contains alkyne group for copper-catalyzed azide-alkyne cycloaddition.
- Enables quantitative and site-specific chemoproteomic profiling.
- Functions as a structural analogue of itaconate with comparable anti-inflammatory effects.
- High purity solid form for reliable experimental results.
- Available in multiple small-scale packaging sizes suitable for laboratory use.
- Compatible with standard click-chemistry reagents and protocols.
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Medchemexpress LLC Ethyl acetoacetate-13C | 61973-42-0 | 98.6% | 131.13 | 100 MG
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Ethyl acetoacetate-13C is a 13C labeled ester extensively used as an intermediate in the synthesis of various compounds. It is also identified as an inhibitor of bacterial biofilm, and can be utilized as a tracer and an internal standard for quantitative analysis via methods such as NMR, GC-MS, or LC-MS.
- Used as a tracer
- Serves as an internal standard for quantitative analysis
- Incorporates carbon-13, a stable heavy isotope, for quantitation during drug development
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Medchemexpress LLC Ethyl palmitate | 628-97-7 | 50 G
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Ethyl palmitate (Ethyl hexadecanoate) is a Chikungunya virus (CHIKV) inhibitor with an EC50 value of 0.0068 μM. It demonstrates anti-inflammatory activity by reducing levels of TNF-α, IL-6, and NF-κB.
- Inhibits expression and viral activity of CHIKV virus E2 protein.
- Reduces plasma levels of TNF-α and IL-6 in endotoxemic rats.
- Decreases NF-κB expression in liver and lung tissues.
- Ameliorates histopathological changes caused by LPS in a rat model of endotoxemia.
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Cayman Chemical Betamethason 17-valerate 500mg
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A glucocorticoid with anti-inflammatory activity; inhibits the binding of the radiolabeled glucocorticoid dexamethasone to human epidermis and mouse skin (IC50s = 5 and 6 nM, respectively); topical application of a 0.12% ointment blocks increases in EAr weight in a rat model of EAr edema induced by croton oil
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Medchemexpress LLC Mk-0812 succinate | 851916-42-2 | 99.94% | C28H40F3N3O7 | 100 MG
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MK-0812 Succinate is a potent and selective CCR2 antagonist with high affinity. It completely blocks all MCP-1 mediated responses in a concentration-dependent manner. It also inhibits 125I-MCP-1 binding on isolated monocytes. The compound blocks the shape change response to exogenous MCP-1 and reduces the frequency of Ly6G-Ly6Chi monocytes in peripheral blood in vivo.
- Potent and selective CCR2 antagonist
- High affinity at CCR2
- Blocks all MCP-1 mediated responses
- Inhibits 125I-MCP-1 binding on isolated monocytes
- Reduces Ly6G-Ly6Chi monocytes in peripheral blood in vivo
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eMolecules 7425-53-8 | Ethyl 4-iodobutyrate | Combi-Blocks | MFCD00045325 | 242.056 | C6H11IO2 | 98.000 | CCOC(=O)CCCI | 5g | 415497677
Ethyl 4-iodobutyrate | Combi-Blocks | 7425-53-8 | MFCD00045325 | 242.056 | C6H11IO2 | 98.000 | CCOC(=O)CCCI | 5g | 415497677
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000431545 PICOLINIC ACID STAN 50MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000267094 ETHYL ACETOACETATE-D 5MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000267093 ETHYL ACETOACETATE-D 50MG
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Medchemexpress LLC Resorufin butyrate 25mg | 15585-42-9 | 25 MG
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Resorufin butyrate is a fluorogenic substrate used to measure triglyceride lipase and cholinesterase activity. Upon enzymatic hydrolysis the ester is converted to resorufin, which is highly fluorescent (Ex 570 nm, Em 580 nm). Supplied as a 25 mg solid for research use, it is suitable for fluorescence-based enzyme assays and assay development.
- Fluorogenic substrate for triglyceride lipases and cholinesterase.
- Generates resorufin detectable at excitation 570 nm and emission 580 nm.
- High purity (99.0%) supports reproducible assay results.
- Stable when stored sealed at -20°C; extended stability in solvent at -80°C.
- Available in multiple package sizes to support assay optimization.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000429775 PICOLINIC ACID STAN 100MG
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eMolecules 1002-62-6 | Sodium Decanoate | Ambeed | MFCD00066453 | 194.250 | C10H19NaO2 | 98.000 | [Na+].CCCCCCCCCC([O-])=O | 5g | 588342773
Sodium Decanoate | Ambeed | 1002-62-6 | MFCD00066453 | 194.250 | C10H19NaO2 | 98.000 | [Na+].CCCCCCCCCC([O-])=O | 5g | 588342773
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eMolecules 105-45-3 | Methyl acetoacetate | Combi-Blocks | MFCD00008784 | 116.116 | C5H8O3 | 95.000 | COC(=O)CC(C)=O | 1kg | 517025978
Methyl acetoacetate | Combi-Blocks | 105-45-3 | MFCD00008784 | 116.116 | C5H8O3 | 95.000 | COC(=O)CC(C)=O | 1kg | 517025978
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Medchemexpress LLC Phorbol 12-myristate 13-acetate | 16561-29-8 | 99.8% | 616.83 | 100 MG
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Phorbol 12-myristate 13-acetate (PMA), also known as TPA or Phorbol myristate acetate, is a phorbol ester. It acts as a dual SphK and protein kinase C (PKC) activator, and also functions as a NF-κB activator. PMA induces differentiation in THP-1 cells and is known to induce a pronounced inflammatory response mediated by protein kinase C (PKC), specifically by activating PLA2.
- Dual SphK and protein kinase C activator
- NF-κB activator
- Induces differentiation in THP-1 cells
- IC₅₀ for PKC is 11.7 nM (EC50)
- Inhibits endothelial cell migration through activating the PKC-δ/Syk/NF-κB-mediated up-regulation of Thy-1
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